Visual inspection time in Parkinson's disease: deficits in early stages of cognitive processing
Identifieur interne : 002C89 ( Main/Exploration ); précédent : 002C88; suivant : 002C90Visual inspection time in Parkinson's disease: deficits in early stages of cognitive processing
Auteurs : Andrew M. Johnson [Canada] ; Quincy J. Almeida [Canada] ; Con Stough [Australie] ; James C. Thompson [Australie] ; Rene Singarayer [Canada] ; Mandar S. Jog [Canada]Source :
- Neuropsychologia [ 0028-3932 ] ; 2004.
Descripteurs français
- Pascal (Inist)
- Wicri :
- topic : Adulte, Personne âgée.
English descriptors
- KwdEn :
- Adult, Aged, Aged, 80 and over, Cognition (physiology), Cognition Disorders (etiology), Cognitive disorder, Elderly, Female, Humans, Information processing, Intelligence Tests, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Parkinson Disease (complications), Parkinson disease, Perception, Psychomotor Performance (physiology), Time Perception (physiology), Velocity, Vision, Visual Perception (physiology).
- MESH :
- complications : Parkinson Disease.
- etiology : Cognition Disorders.
- physiology : Cognition, Psychomotor Performance, Time Perception, Visual Perception.
- Adult, Aged, Aged, 80 and over, Female, Humans, Intelligence Tests, Male, Mental Status Schedule, Middle Aged, Neuropsychological Tests.
Abstract
Inspection time (IT) is a simple information processing paradigm dependent on a participant's ability to identify physical properties of a stimulus presented for a specified time interval. In contrast with reaction time (RT) studies, the dependent variable of interest in IT is not related to the motoric speed with which the individual is able to respond, but rather the minimum presentation time necessary for participants to reliably identify physical properties of the stimulus. It is well documented that individuals with Parkinson's disease (PD) experience significant impairment on tests of simple RT, but it is unclear whether such deficits can be interpreted as 'pure' slowness of information processing, or a delay in the selection and output of a motor response. In the first experiment described here, a sample of 'optimally medicated' PD patients was compared with an age-matched control group, on an IT task. Results of this experiment suggested that individuals with PD required significantly longer stimulus presentation times than healthy participants. The second experiment compared a sample of PD patients (tested both "ON" and "OFF" their typical dopaminergic medications), with an age-matched control group, on the same test of IT. Results again indicated a significant IT deficit in participants with PD, and suggested that these deficits do not significantly resolve with levodopa treatment. Overall, the results of these two experiments suggest that information processing deficits associated with PD are distinct from motor impairment. These findings are further discussed in terms of existing neurochemical models of information processing ability.
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000A13
- to stream PascalFrancis, to step Curation: 000310
- to stream PascalFrancis, to step Checkpoint: 000829
- to stream Main, to step Merge: 003051
- to stream PubMed, to step Corpus: 001390
- to stream PubMed, to step Curation: 001390
- to stream PubMed, to step Checkpoint: 001390
- to stream Ncbi, to step Merge: 000390
- to stream Ncbi, to step Curation: 000390
- to stream Ncbi, to step Checkpoint: 000390
- to stream Main, to step Merge: 002E95
- to stream Main, to step Curation: 002C89
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Visual inspection time in Parkinson's disease: deficits in early stages of cognitive processing</title>
<author><name sortKey="Johnson, Andrew M" sort="Johnson, Andrew M" uniqKey="Johnson A" first="Andrew M." last="Johnson">Andrew M. Johnson</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Faculty of Health Sciences, University of Western Ontario</s1>
<s2>London, Ont., N6A 3K7</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont., N6A 3K7</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of kinesiology University of Waterloo</s1>
<s2>Waterloo, Ont</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Department of kinesiology University of Waterloo</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Neurological Sciences, London Health Sciences Centre</s1>
<s2>London, Ont.</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stough, Con" sort="Stough, Con" uniqKey="Stough C" first="Con" last="Stough">Con Stough</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Swinburne Centre for Neuropsychology, Swinburne University</s1>
<s2>Hawthorn, Vic.</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Hawthorn, Vic.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Thompson, James C" sort="Thompson, James C" uniqKey="Thompson J" first="James C." last="Thompson">James C. Thompson</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Swinburne Centre for Neuropsychology, Swinburne University</s1>
<s2>Hawthorn, Vic.</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Hawthorn, Vic.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Singarayer, Rene" sort="Singarayer, Rene" uniqKey="Singarayer R" first="Rene" last="Singarayer">Rene Singarayer</name>
<affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Department of Biochemistry, McGill University</s1>
<s2>Montreal, Que</s2>
<s3>CAN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
<orgName type="university">Université McGill</orgName>
</affiliation>
</author>
<author><name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Neurological Sciences, London Health Sciences Centre</s1>
<s2>London, Ont.</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont.</wicri:noRegion>
</affiliation>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">INIST</idno>
<idno type="inist">04-0164588</idno>
<date when="2004">2004</date>
<idno type="stanalyst">PASCAL 04-0164588 INIST</idno>
<idno type="RBID">Pascal:04-0164588</idno>
<idno type="wicri:Area/PascalFrancis/Corpus">000A13</idno>
<idno type="wicri:Area/PascalFrancis/Curation">000310</idno>
<idno type="wicri:Area/PascalFrancis/Checkpoint">000829</idno>
<idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000829</idno>
<idno type="wicri:doubleKey">0028-3932:2004:Johnson A:visual:inspection:time</idno>
<idno type="wicri:Area/Main/Merge">003051</idno>
<idno type="wicri:source">PubMed</idno>
<idno type="RBID">pubmed:14725796</idno>
<idno type="wicri:Area/PubMed/Corpus">001390</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">001390</idno>
<idno type="wicri:Area/PubMed/Curation">001390</idno>
<idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">001390</idno>
<idno type="wicri:Area/PubMed/Checkpoint">001390</idno>
<idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">001390</idno>
<idno type="wicri:Area/Ncbi/Merge">000390</idno>
<idno type="wicri:Area/Ncbi/Curation">000390</idno>
<idno type="wicri:Area/Ncbi/Checkpoint">000390</idno>
<idno type="wicri:doubleKey">0028-3932:2004:Johnson A:visual:inspection:time</idno>
<idno type="wicri:Area/Main/Merge">002E95</idno>
<idno type="wicri:Area/Main/Curation">002C89</idno>
<idno type="wicri:Area/Main/Exploration">002C89</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Visual inspection time in Parkinson's disease: deficits in early stages of cognitive processing</title>
<author><name sortKey="Johnson, Andrew M" sort="Johnson, Andrew M" uniqKey="Johnson A" first="Andrew M." last="Johnson">Andrew M. Johnson</name>
<affiliation wicri:level="1"><inist:fA14 i1="01"><s1>Faculty of Health Sciences, University of Western Ontario</s1>
<s2>London, Ont., N6A 3K7</s2>
<s3>CAN</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont., N6A 3K7</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name>
<affiliation wicri:level="1"><inist:fA14 i1="02"><s1>Department of kinesiology University of Waterloo</s1>
<s2>Waterloo, Ont</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>Department of kinesiology University of Waterloo</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Neurological Sciences, London Health Sciences Centre</s1>
<s2>London, Ont.</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Stough, Con" sort="Stough, Con" uniqKey="Stough C" first="Con" last="Stough">Con Stough</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Swinburne Centre for Neuropsychology, Swinburne University</s1>
<s2>Hawthorn, Vic.</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Hawthorn, Vic.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Thompson, James C" sort="Thompson, James C" uniqKey="Thompson J" first="James C." last="Thompson">James C. Thompson</name>
<affiliation wicri:level="1"><inist:fA14 i1="04"><s1>Swinburne Centre for Neuropsychology, Swinburne University</s1>
<s2>Hawthorn, Vic.</s2>
<s3>AUS</s3>
<sZ>3 aut.</sZ>
<sZ>4 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Hawthorn, Vic.</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Singarayer, Rene" sort="Singarayer, Rene" uniqKey="Singarayer R" first="Rene" last="Singarayer">Rene Singarayer</name>
<affiliation wicri:level="4"><inist:fA14 i1="05"><s1>Department of Biochemistry, McGill University</s1>
<s2>Montreal, Que</s2>
<s3>CAN</s3>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<placeName><settlement type="city">Montréal</settlement>
<region type="state">Québec</region>
</placeName>
<orgName type="university">Université McGill</orgName>
</affiliation>
</author>
<author><name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
<affiliation wicri:level="1"><inist:fA14 i1="03"><s1>Department of Clinical Neurological Sciences, London Health Sciences Centre</s1>
<s2>London, Ont.</s2>
<s3>CAN</s3>
<sZ>2 aut.</sZ>
<sZ>6 aut.</sZ>
</inist:fA14>
<country>Canada</country>
<wicri:noRegion>London, Ont.</wicri:noRegion>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">Neuropsychologia</title>
<title level="j" type="abbreviated">Neuropsychologia</title>
<idno type="ISSN">0028-3932</idno>
<imprint><date when="2004">2004</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">Neuropsychologia</title>
<title level="j" type="abbreviated">Neuropsychologia</title>
<idno type="ISSN">0028-3932</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Cognition (physiology)</term>
<term>Cognition Disorders (etiology)</term>
<term>Cognitive disorder</term>
<term>Elderly</term>
<term>Female</term>
<term>Humans</term>
<term>Information processing</term>
<term>Intelligence Tests</term>
<term>Male</term>
<term>Mental Status Schedule</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
<term>Parkinson Disease (complications)</term>
<term>Parkinson disease</term>
<term>Perception</term>
<term>Psychomotor Performance (physiology)</term>
<term>Time Perception (physiology)</term>
<term>Velocity</term>
<term>Vision</term>
<term>Visual Perception (physiology)</term>
</keywords>
<keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term>
</keywords>
<keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Cognition Disorders</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Cognition</term>
<term>Psychomotor Performance</term>
<term>Time Perception</term>
<term>Visual Perception</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Adult</term>
<term>Aged</term>
<term>Aged, 80 and over</term>
<term>Female</term>
<term>Humans</term>
<term>Intelligence Tests</term>
<term>Male</term>
<term>Mental Status Schedule</term>
<term>Middle Aged</term>
<term>Neuropsychological Tests</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Parkinson maladie</term>
<term>Vitesse</term>
<term>Traitement information</term>
<term>Perception</term>
<term>Vision</term>
<term>Trouble cognition</term>
<term>Adulte</term>
<term>Personne âgée</term>
<term>Temps inspection</term>
</keywords>
<keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Adulte</term>
<term>Personne âgée</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Inspection time (IT) is a simple information processing paradigm dependent on a participant's ability to identify physical properties of a stimulus presented for a specified time interval. In contrast with reaction time (RT) studies, the dependent variable of interest in IT is not related to the motoric speed with which the individual is able to respond, but rather the minimum presentation time necessary for participants to reliably identify physical properties of the stimulus. It is well documented that individuals with Parkinson's disease (PD) experience significant impairment on tests of simple RT, but it is unclear whether such deficits can be interpreted as 'pure' slowness of information processing, or a delay in the selection and output of a motor response. In the first experiment described here, a sample of 'optimally medicated' PD patients was compared with an age-matched control group, on an IT task. Results of this experiment suggested that individuals with PD required significantly longer stimulus presentation times than healthy participants. The second experiment compared a sample of PD patients (tested both "ON" and "OFF" their typical dopaminergic medications), with an age-matched control group, on the same test of IT. Results again indicated a significant IT deficit in participants with PD, and suggested that these deficits do not significantly resolve with levodopa treatment. Overall, the results of these two experiments suggest that information processing deficits associated with PD are distinct from motor impairment. These findings are further discussed in terms of existing neurochemical models of information processing ability.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>Canada</li>
</country>
<region><li>Québec</li>
</region>
<settlement><li>Montréal</li>
</settlement>
<orgName><li>Université McGill</li>
</orgName>
</list>
<tree><country name="Canada"><noRegion><name sortKey="Johnson, Andrew M" sort="Johnson, Andrew M" uniqKey="Johnson A" first="Andrew M." last="Johnson">Andrew M. Johnson</name>
</noRegion>
<name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name>
<name sortKey="Almeida, Quincy J" sort="Almeida, Quincy J" uniqKey="Almeida Q" first="Quincy J." last="Almeida">Quincy J. Almeida</name>
<name sortKey="Jog, Mandar S" sort="Jog, Mandar S" uniqKey="Jog M" first="Mandar S." last="Jog">Mandar S. Jog</name>
<name sortKey="Singarayer, Rene" sort="Singarayer, Rene" uniqKey="Singarayer R" first="Rene" last="Singarayer">Rene Singarayer</name>
</country>
<country name="Australie"><noRegion><name sortKey="Stough, Con" sort="Stough, Con" uniqKey="Stough C" first="Con" last="Stough">Con Stough</name>
</noRegion>
<name sortKey="Thompson, James C" sort="Thompson, James C" uniqKey="Thompson J" first="James C." last="Thompson">James C. Thompson</name>
</country>
</tree>
</affiliations>
</record>
Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 002C89 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 002C89 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien |wiki= Wicri/Canada |area= ParkinsonCanadaV1 |flux= Main |étape= Exploration |type= RBID |clé= Pascal:04-0164588 |texte= Visual inspection time in Parkinson's disease: deficits in early stages of cognitive processing }}
This area was generated with Dilib version V0.6.29. |